Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18585884 | 0.98 | NOS1 (0.47) | NOS1FBP1ADRB2ADRB1ADRB3 | |
| SCHEMBL8292234 | 0.78 | — | — | |
| SCHEMBL3150281 | 0.77 | NOS1 (0.41) | NOS1FBP1ADRB2ADRB1ADRB3 | |
| SCHEMBL11686761 | 0.74 | NOS1 (0.61) | NOS1FBP1ELANE | |
| SCHEMBL14275238 | 0.74 | — | — | |
| SCHEMBL8279060 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL2378439 | 0.73 | NOS1 (0.59) | NOS1FBP1 | |
| SCHEMBL21122903 | 0.71 | NOS1 (0.55) | NOS1FBP1ELANE | |
| SCHEMBL23879317 | 0.70 | NOS1 (0.46) | NOS1FBP1ELANE | |
| SCHEMBL12428566 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158516-A1 | IRE1α MODULATORS AND USES THEREOF | NIMBUS IASO, INC. (US) | 2021-08-12 | — | — | WO | disclosed |