Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13282148 | 0.83 | — | — | |
| SCHEMBL10125881 | 0.74 | ALDH1A1 (0.41) | ALDH1A1LMNASLC15A2ARG1ARG2 | |
| SCHEMBL24729166 | 0.73 | — | — | |
| SCHEMBL13662526 | 0.72 | PAOX (0.48) | ALDH1A1LMNASLC15A2TDP1 | |
| SCHEMBL23874295 | 0.72 | KDM4E (0.43) | ALDH1A1TDP1 | |
| SCHEMBL19849367 | 0.72 | ALDH1A1 (0.48) | ALDH1A1LMNASLC15A2 | |
| SCHEMBL25090250 | 0.71 | PAOX (0.52) | ALDH1A1 | |
| SCHEMBL25453230 | 0.71 | PAOX (0.52) | ALDH1A1 | |
| SCHEMBL23729381 | 0.71 | PAOX (0.52) | ALDH1A1 | |
| SCHEMBL22327372 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |