Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | IDH1 | O75874 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23747405 | 0.84 | LSS (0.70) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747450 | 0.84 | RAB9A (0.52) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747781 | 0.81 | CYP1A2 (0.49) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747782 | 0.76 | LSS (0.67) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747399 | 0.74 | LSS (0.69) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747729 | 0.74 | RAB9A (0.69) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747492 | 0.74 | LSS (0.76) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747754 | 0.73 | LSS (0.78) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747418 | 0.71 | RAB9A (0.78) | RAB9APOLBLSSNPC1NAMPT | |
| SCHEMBL23747639 | 0.71 | RAB9A (0.78) | RAB9APOLBLSSNPC1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |