Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24849599 | 0.84 | TYR (0.42) | ALDH1A1HTTHIF1AGAAALOX12 | |
| Ammonia Solution, Strong SCHEMBL28370828 | 0.78 | MAPT (0.50) | ALDH1A1MEN1MAPTKMT2AHTT | |
| SCHEMBL28874180 | 0.78 | TAAR1 (0.50) | ALDH1A1KMT2ATDP1L3MBTL1KDM4E | |
| SCHEMBL5955 | 0.75 | MAPT (0.53) | ALDH1A1MEN1MAPTKMT2AHTT | |
| SCHEMBL19304127 | 0.75 | ESR1 (0.56) | ALDH1A1MEN1MAPTKMT2AHIF1A | |
| SCHEMBL23837663 | 0.75 | CYP2A6 (0.40) | ALDH1A1CYP3A4POLBHSD17B10HPGD | |
| SCHEMBL1145645 | 0.75 | ADRB2 (0.52) | HIF1AMAPK1TSHRTDP1TP53 | |
| SCHEMBL20809867 | 0.74 | KMT2A (0.44) | ALDH1A1KMT2AHIF1ACYP3A4TSHR | |
| SCHEMBL14535430 | 0.74 | KMT2A (0.44) | ALDH1A1KMT2AHIF1ACYP3A4TSHR | |
| SCHEMBL1145689 | 0.74 | KMT2A (0.44) | ALDH1A1KMT2AHIF1ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |