Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099423 | 0.90 | RAB9A (0.53) | HPGDCHRM1HTR2AMCHR1RAB9A | |
| SCHEMBL26098898 | 0.90 | RAB9A (0.53) | HPGDCHRM1HTR2AMCHR1RAB9A | |
| SCHEMBL26102746 | 0.85 | HPGD (0.48) | HPGDALOX5HRH3MAPTRAB9A | |
| SCHEMBL26103046 | 0.85 | HPGD (0.48) | HPGDALOX5HRH3MAPTRAB9A | |
| SCHEMBL26098540 | 0.84 | CHRM1 (0.53) | HPGDCHRM1HTR2AMCHR1HRH3 | |
| SCHEMBL23747606 | 0.84 | CHRM1 (0.53) | HPGDCHRM1HTR2AMCHR1HRH3 | |
| SCHEMBL26102617 | 0.80 | RAB9A (0.53) | RAB9APOLBNPC1ALDH1A1 | |
| SCHEMBL26097964 | 0.80 | RAB9A (0.53) | RAB9APOLBNPC1ALDH1A1 | |
| SCHEMBL26103379 | 0.79 | HPGD (0.52) | HPGDHRH3MAPTNPC1 | |
| SCHEMBL26102133 | 0.78 | CHRM1 (0.49) | CHRM1HTR2AMCHR1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |