SCHEMBL2374837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12231898	0.91	NAMPT (0.41)	IKBKBCDK2SRCPDGFRBABL1
	SCHEMBL2375240	0.89	KMT2A (0.44)	IKBKBCDK2PLK1PLK3PLK2
	SCHEMBL29430194	0.89	RET (0.41)	IKBKBCDK2CCNT1CCNA2CDK7
	SCHEMBL901103	0.89	RET (0.41)	IKBKBCDK2CCNT1CCNA2CDK7
	SCHEMBL2373916	0.89	ROCK1 (0.43)	CDK2PLK1PLK3PLK2SYK
	SCHEMBL2375780	0.87	ROCK1 (0.53)	IKBKBCDK2CCNT1CDK7CDK9
	SCHEMBL31681850	0.86	SYK (0.42)	PLK1PLK3PLK2SYKSRC
	SCHEMBL2374300	0.86	SYK (0.42)	PLK1PLK3PLK2SYKSRC
	SCHEMBL13911407	0.83	IKBKB (0.50)	IKBKBCDK2CCNT1CCNA2CDK7
	SCHEMBL20684532	0.83	ROCK1 (0.36)	CDK7PLK1SYKPDGFRBABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.