Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CCNH | P51946 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | SMG1 | Q96Q15 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | IKBKB | O14920 | 7/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | DKK1 | O94907 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373916 | 0.89 | ROCK1 (0.43) | ROCK1CA1CA2CA7CA9 | |
| SCHEMBL16073019 | 0.87 | IKBKB (0.55) | ROCK1CA1CA2CA9CA14 | |
| SCHEMBL31681850 | 0.87 | SYK (0.42) | ROCK1JAK2 | |
| SCHEMBL2374300 | 0.87 | SYK (0.42) | ROCK1JAK2 | |
| SCHEMBL17951061 | 0.87 | ROCK1 (0.41) | ROCK1CA1CA2CA7CA9 | |
| SCHEMBL2374837 | 0.87 | IKBKB (0.49) | ROCK1CA2CA9CCNT1CDK7 | |
| SCHEMBL2373964 | 0.85 | ROCK1 (0.48) | ROCK1CDK1SMG1IKBKBCDK2 | |
| SCHEMBL31681831 | 0.85 | ROCK1 (0.48) | ROCK1CDK1SMG1IKBKBCDK2 | |
| SCHEMBL20684574 | 0.85 | ROCK1 (0.42) | ROCK1CDK7JAK2FLT3GSK3B | |
| SCHEMBL901103 | 0.84 | RET (0.41) | ROCK1CCNT1CDK7CDK9CCNH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | THE SCRIPPS RESEARCH INSTITUTE (US) | 2025-09-09 | — | — | US | disclosed |
| EP-4585589-A2 | STEM CELL CULTURES | The Scripps Research Institute (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-4296270-B1 | A COMPOSITION COMPRISING STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-4296270-A2 | A COMPOSITION COMPRISING STEM CELL CULTURES | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3936508-B1 | A COMPOSITION COMPRISING STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3936508-A1 | A COMPOSITION COMPRISING STEM CELL CULTURES | The Scripps Research Institute (US) | 2022-01-12 | — | — | EP | disclosed |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-12-30 | — | — | US | disclosed |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | THE SCRIPPS RESEARCH INSTITUTE | 2021-12-30 | — | — | US | disclosed |
| EP-3623374-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3623374-B1 | STEM CELL CULTURES | SCRIPPS RESEARCH INST (US) | 2021-09-08 | — | — | EP | disclosed |
| US-20110294761-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294761-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294761-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-12-01 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044201-B2 | Stem cell cultures | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-10-25 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224233-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010065721-A1 | STEM CELL CULTURES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294761-A1 | STEM CELL CULTURES | NES, CD44, MCL1 | ROCK1 713/4885CA1 1171/4885CA2 3173/4885 |
| US-12410397-B2 | Methods of enhancing cell survival of stem cells | MCL1, BCL2, BCLAF1 | ROCK1 2668/4885CA1 1125/4885CA2 3582/4885 |
| US-20210403862-A1 | METHODS OF ENHANCING CELL SURVIVAL OF STEM CELLS | MCL1, BCL2, BCLAF1 | ROCK1 2668/4885CA1 1125/4885CA2 3582/4885 |
| US-20110224233-A1 | STEM CELL CULTURES | NES, CD44, MCL1 | ROCK1 713/4885CA1 1171/4885CA2 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.