Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 11/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24120405 | 0.92 | HDAC1 (0.44) | HDAC2HDAC1HDAC3EGFRCNR1 | |
| SCHEMBL21361289 | 0.89 | HDAC2 (0.42) | HDAC2HDAC1HDAC3ABCG2ROCK2 | |
| SCHEMBL24120333 | 0.88 | HDAC1 (0.40) | HDAC2HDAC1HDAC3CNR1CNR2 | |
| SCHEMBL24120304 | 0.88 | HDAC2 (0.40) | HDAC2HDAC1HDAC3CNR1CNR2 | |
| SCHEMBL24120384 | 0.88 | HDAC2 (0.37) | HDAC2HDAC1HDAC3EGFRCNR1 | |
| SCHEMBL24120397 | 0.88 | HDAC2 (0.37) | HDAC2HDAC1HDAC3EGFRCNR1 | |
| SCHEMBL24120371 | 0.87 | HDAC2 (0.37) | HDAC2HDAC1HDAC3 | |
| SCHEMBL24120269 | 0.87 | HDAC2 (0.36) | HDAC2HDAC1HDAC3EGFRCNR1 | |
| SCHEMBL24120106 | 0.87 | HDAC2 (0.38) | HDAC2HDAC1HDAC3EGFRCNR1 | |
| SCHEMBL24120357 | 0.86 | HSD11B1 (0.42) | HDAC2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | SYNGENTA CROP PROTECTION AG (CH) | 2025-08-26 | — | — | US | disclosed |
| CN-112823150-B | Herbicidal 2-azaspiro [3-5] nonane compounds | 先正达农作物保护股份公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-3864006-B1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-11-16 | — | — | EP | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-23 | — | — | US | disclosed |
| EP-3864006-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2021-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395196-A1 | HERBICIDAL 2-AZASPIRO[3-5]NONANE COMPOUNDS | DDT, AZI2, CBR3 | HDAC2 490/4885HDAC1 246/4885HDAC3 398/4885 |
| US-12398101-B2 | Herbicidal 2-azaspiro[3-5]nonane compounds | DDT, AZI2, CBR3 | HDAC2 490/4885HDAC1 246/4885HDAC3 398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.