SCHEMBL23748432

SCHEMBL23748432

CCCCCCC(C)OC(=O)N(C)C

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.54
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
ALDH1A1 P00352 1/20 0.48
NAAA Q02083 1/20 0.43
LMNA P02545 2/20 0.43
ACE2 Q9BYF1 1/20 0.42
KDM4E B2RXH2 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GPR84 Q9NQS5 3/20 0.41
FFAR1 O14842 1/20 0.41
CA1 P00915 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2535553 0.84 FAAH (0.41) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL10836618 0.84 FAAH (0.57) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL10836646 0.84 FAAH (0.57) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL29023837 0.84 FAAH (0.53) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL8989555 0.82 FAAH (0.51) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL8968820 0.82 FAAH (0.51) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL7522458 0.82 FAAH (0.51) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL20260562 0.82 FAAH (0.41) FAAHCNR1CNR2ALDH1A1LMNA
SCHEMBL11231380 0.82 FAAH (0.50) FAAHCNR1CNR2ALDH1A1NAAA
SCHEMBL2536838 0.81 FAAH (0.39) FAAHCNR1CNR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4209483-A1 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2023-07-12 EP disclosed
CN-116283647-A Prodrug modulators that integrate stress pathways 卡里科生命科学有限责任公司 2023-06-23 CN disclosed
EP-3864003-A1 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2021-08-18 EP disclosed