SCHEMBL23748664

SCHEMBL23748664

CCCCCNc1cccc(C(=O)O)c1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 4/20 0.50
CNR1 P21554 1/20 0.50
KDM6B O15054 1/20 0.50
KDM4C Q9H3R0 1/20 0.50
PLK1 P53350 4/20 0.49
CA12 O43570 1/20 0.49
CA9 Q16790 1/20 0.49
HPGD P15428 2/20 0.48
CYP2C9 P11712 1/20 0.48
HSD17B10 Q99714 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MAPK8 P45983 1/20 0.46
CISD1 Q9NZ45 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5136114 0.98 PLK1 (0.51) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL2382976 0.88 CNR2 (0.50) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL27736211 0.88 KDM6B (0.52) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL27756887 0.86 PLK1 (0.52) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL466141 0.86 PLK1 (0.63) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL23748672 0.85 KDM4E (0.52) CNR2CNR1KDM4EALDH1A1
SCHEMBL28310186 0.85 CNR2 (0.50) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL7603848 0.85 CNR2 (0.50) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL11443814 0.84 PLK1 (0.66) CNR2CNR1KDM6BKDM4CPLK1
SCHEMBL11432358 0.84 PLK1 (0.66) CNR2CNR1KDM6BKDM4CPLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof BASF AS (NO) 2025-11-18 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
EP-3864001-A1 ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-08-18 EP disclosed
CN-113166024-A Aromatic compounds and their medical use 巴斯夫股份公司 2021-07-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof GLS2, FFAR3, SLC10A1 CNR2 102/4885CNR1 74/4885KDM6B 837/4885
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF GLS2, FFAR3, SLC10A1 CNR2 102/4885CNR1 74/4885KDM6B 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.