SCHEMBL23748672

SCHEMBL23748672

CCCCCNc1cccc(C(=O)OC)c1C

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
GLA P06280 1/20 0.52
RIPK1 Q13546 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
CNR2 P34972 4/20 0.48
CNR1 P21554 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
ALDH1A1 P00352 4/20 0.47
KMT2A Q03164 2/20 0.47
ALOX12 P18054 1/20 0.47
LMNA P02545 2/20 0.46
POLB P06746 1/20 0.44
ATM Q13315 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5928710 0.87 KDM4E (0.69) KDM4EGLARIPK1SMN1; SMN2CYP1A2
SCHEMBL28807971 0.86 KDM4E (0.52) KDM4EGLARIPK1SMN1; SMN2CYP1A2
SCHEMBL2382707 0.86 KDM4E (0.52) KDM4EGLARIPK1SMN1; SMN2CYP1A2
SCHEMBL28038888 0.85 CNR2 (0.44) KDM4EGLACNR2CNR1ALDH1A1
SCHEMBL28039144 0.85 CNR2 (0.44) KDM4EGLACNR2CNR1ALDH1A1
SCHEMBL28823422 0.85 CNR2 (0.44) KDM4EGLACNR2CNR1ALDH1A1
SCHEMBL28039136 0.85 CNR2 (0.44) KDM4EGLACNR2CNR1ALDH1A1
SCHEMBL29047146 0.85 KDM4E (0.68) KDM4EGLARIPK1SMN1; SMN2CYP1A2
SCHEMBL5272294 0.85 KDM4E (0.68) KDM4EGLARIPK1SMN1; SMN2CYP1A2
SCHEMBL23748664 0.85 CNR2 (0.50) KDM4ECNR2CNR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof BASF AS (NO) 2025-11-18 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-12-09 US disclosed
EP-3864001-A1 ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF BASF AS (NO) 2021-08-18 EP disclosed
CN-113166024-A Aromatic compounds and their medical use 巴斯夫股份公司 2021-07-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12473249-B2 Aromatic compounds and pharmaceutical uses thereof GLS2, FFAR3, SLC10A1 KDM4E 1204/4885GLA 732/4885RIPK1 3250/4885
US-20210380521-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF GLS2, FFAR3, SLC10A1 KDM4E 1204/4885GLA 732/4885RIPK1 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.