Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627299 | 1.00 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23748607 | 0.81 | CYP3A4 (0.38) | CYP3A4MAPK1SMN1; SMN2PTGS1PLA2G2A | |
| SCHEMBL23748610 | 0.81 | CYP3A4 (0.38) | CYP3A4MAPK1SMN1; SMN2PTGS1PLA2G2A | |
| SCHEMBL23748719 | 0.77 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL23748716 | 0.77 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL466144 | 0.74 | CYP3A4 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL24087411 | 0.73 | CYP3A4 (0.46) | CYP3A4MAPK1SMN1; SMN2KMT2A | |
| SCHEMBL23748627 | 0.71 | PLA2G4B (0.54) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23748660 | 0.71 | PLA2G4B (0.54) | TSHRMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10452299 | 0.71 | PLA2G4B (0.54) | TSHRMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-12-09 | — | — | US | disclosed |
| EP-3864001-A1 | ROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | BASF AS (NO) | 2021-08-18 | — | — | EP | disclosed |
| CN-113166024-A | Aromatic compounds and their medical use | 巴斯夫股份公司 | 2021-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380521-A1 | AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | GLS2, FFAR3, SLC10A1 | CA12 1054/4885CA1 1272/4885CA2 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.