SCHEMBL466144

SCHEMBL466144

COc1cc(OC)c(C(=O)O)c(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.60
MAPK1 P28482 2/20 0.60
USP2 O75604 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
CA12 O43570 2/20 0.59
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
ABCG2 Q9UNQ0 2/20 0.53
LMNA P02545 1/20 0.51
KMT2A Q03164 3/20 0.49
MKNK2 Q9HBH9 1/20 0.48
MAPT P10636 2/20 0.47
TP53 P04637 1/20 0.47
ATM Q13315 1/20 0.47
HSD17B10 Q99714 1/20 0.47
CA3 P07451 1/20 0.47
PKM P14618 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225545 0.88 CYP3A4 (0.53) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL1614609 0.88 CYP3A4 (0.73) CYP3A4MAPK1USP2SMN1; SMN2ABCG2
SCHEMBL6507929 0.88 SMN1; SMN2 (0.53) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL311761 0.88 KMT2A (0.57) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL1012409 0.86 CYP3A4 (0.51) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL31335763 0.86 CYP3A4 (0.51) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL18170324 0.86 MAPK1 (0.51) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL30486448 0.85 CYP3A4 (0.50) CYP3A4MAPK1USP2SMN1; SMN2CA12
SCHEMBL29109689 0.85 CYP3A4 (0.50) CYP3A4MAPK1USP2SMN1; SMN2CA12
Hydrochloric Acid SCHEMBL4299984 0.85 CYP3A4 (0.50) CYP3A4MAPK1USP2SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924306-A Full-synthesis preparation method of wedelolactone or demethylwedelolactone 中国药科大学 2024-04-26 CN claimed
CN-117343615-A Water-based UV positioning laser transfer coating and preparation method and application thereof 湖南互力达涂料科技有限公司 2024-01-05 CN claimed
CN-116041319-B Preparation method of indolyl tetrahydroisoquinoline derivative 江苏中利集团股份有限公司 2023-08-25 CN claimed
CN-116041319-A Preparation method of indolyl tetrahydroisoquinoline derivative 江苏中利集团股份有限公司 2023-05-02 CN claimed
CN-106748604-B Method for synthesizing mono-iodo aromatic hydrocarbon or di-iodo aromatic hydrocarbon based on decarboxylation of aromatic carboxylic acid 湘潭大学 2020-06-05 CN claimed
CN-106748604-A A kind of method for synthesizing single iodo aromatic hydrocarbon or two iodo aromatic hydrocarbons based on aromatic carboxylic acid's decarboxylic reaction 湘潭大学 2017-05-31 CN claimed
US-7196214-B2 Process for arylamine production XEROX CORPORATION (US) 2007-03-27 US claimed
US-20060111582-A1 Process for arylamine production XEROX CORPORATION (US) 2006-05-25 US claimed
US-20040147493-A1 Synergistic compositions for the selective control of tumor tissue KREUTZ WERNER 2004-07-29 US claimed
US-20030166621-A1 Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents KREUTZ WERNER (DE) 2003-09-04 US claimed
EP-1001756-A1 SYNERGISTICALLY ACTING COMPOSITIONS FOR SELECTIVELY COMBATING TUMOR TISSUE Kreutz, Werner, Prof. Dr. (DE) 2000-05-24 EP claimed
WO-1998058639-A1 SYNERGISTICALLY ACTING COMPOSITIONS FOR SELECTIVELY COMBATING TUMOR TISSUE KREUTZ WERNER (DE) 1998-12-30 WO claimed
CN-117924306-B Full-synthesis preparation method of wedelolactone or demethylwedelolactone 中国药科大学 2025-09-16 CN disclosed
CN-118702589-A Method for synthesizing tertiary amide in aqueous phase 常州合全药业有限公司 2024-09-27 CN disclosed
CN-117924306-A Full-synthesis preparation method of wedelolactone or demethylwedelolactone 中国药科大学 2024-04-26 CN disclosed
CN-117924306-A Full-synthesis preparation method of wedelolactone or demethylwedelolactone 中国药科大学 2024-04-26 CN disclosed
US-4247597-A Electroscopic carrier particles having a carboxylic acid surface treatment PITNEY BOWES, INC. (US) 1981-01-27 US disclosed
US-4230696-A CONTAINING GLYCINE AND LYSINE OR ARGININE ST. LUKE'S HOSPITAL (US) 1980-10-28 US disclosed
US-4075167-A MALEIMIDO GROUP-CONTAINING ORGANOSILICON COMPOUNDS DAI NIPPON PRINTING CO., LTD. (JA) 1978-02-21 US disclosed
US-4019904-A INK REPELLENT DAI NIPPON PRINTING COMPANY LIMITED (JA) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111582-A1 Process for arylamine production AOC2, UFM1, TYR CYP3A4 85/4885MAPK1 2706/4885USP2 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.