Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2375316 | 0.93 | TRPV1 (0.40) | CYP24A1TRPV1HTR5AHTR1ADRD2 | |
| SCHEMBL2375311 | 0.93 | TRPV1 (0.40) | CYP24A1TRPV1HTR5AHTR1ADRD2 | |
| SCHEMBL2375324 | 0.93 | TRPV1 (0.40) | CYP24A1TRPV1HTR5AHTR1ADRD2 | |
| SCHEMBL2375859 | 0.91 | CYP26A1 (0.40) | CYP24A1TRPV1TBXAS1CYP1A2USP2 | |
| SCHEMBL2375856 | 0.91 | CYP26A1 (0.40) | CYP24A1TRPV1TBXAS1CYP1A2USP2 | |
| SCHEMBL2376134 | 0.86 | OPRK1 (0.40) | TRPV1HTR2AHDAC1 | |
| SCHEMBL2376137 | 0.86 | OPRK1 (0.40) | TRPV1HTR2AHDAC1 | |
| SCHEMBL1124512 | 0.85 | TRPV1 (0.42) | TRPV1KMT2AHTR5AHTR1ADRD2 | |
| SCHEMBL1124509 | 0.85 | TRPV1 (0.42) | TRPV1KMT2AHTR5AHTR1ADRD2 | |
| SCHEMBL1124510 | 0.85 | TRPV1 (0.42) | TRPV1KMT2AHTR5AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224210-A1 | NOVEL BIS-AMIDES AS ANTI-MALARIAL AGENTS | CTSA, BECN1, HDAC6 | CYP24A1 3780/4885TRPV1 2628/4885TBXAS1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.