SCHEMBL2374932

SCHEMBL2374932

O=Nc1cncc(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.35
MAPT P10636 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
NOX1 Q9Y5S8 2/20 0.31
NOX3 Q9HBY0 1/20 0.31
NOX4 Q9NPH5 1/20 0.31
LMNA P02545 1/20 0.31
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337576 0.73
SCHEMBL1552788 0.72 HTT (0.34) HTTMAPTCDK5CDK5R1NPSR1
SCHEMBL8354714 0.70
SCHEMBL12463823 0.63 S100B (0.47) NPSR1LMNA
SCHEMBL1920495 0.62 HTT (0.33) HTTMAPTCDK5CDK5R1NPSR1
SCHEMBL7905113 0.62
SCHEMBL4363571 0.62
SCHEMBL22764089 0.62 GRK2 (0.33) HTTMAPTNPSR1
SCHEMBL1919936 0.62 TDP1 (0.37) LMNA
SCHEMBL13419065 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2495351-B1 ZINC-COATED STEEL PLATE JFE STEEL CORP (JP) 2018-02-28 EP disclosed
CN-102991023-B The surface treated steel plate that corrosion stability, conductivity and coating appearance are excellent 杰富意钢铁株式会社 2016-08-10 CN disclosed
US-9127366-B2 Zinc-based metal coated steel sheet JFE STEEL CORPORATION (JP) 2015-09-08 US disclosed
EP-2623637-B1 GALVANIZED STEEL SHEET JFE STEEL CORP (JP) 2015-08-26 EP disclosed
US-9051654-B2 Galvanized steel sheet JFE STEEL CORPORATION (JP) 2015-06-09 US disclosed
US-20130302637-A1 ZINC-BASED METAL COATED STEEL SHEET JFE STEEL CORPORATION (JP) 2013-11-14 US disclosed
EP-2623637-A1 GALVANIZED STEEL SHEET JFE Steel Corporation (JP) 2013-08-07 EP disclosed
EP-2495351-A1 ZINC-COATED STEEL PLATE JFE Steel Corporation (JP) 2012-09-05 EP disclosed
US-20120208043-A1 GALVANIZED STEEL SHEET JFE STEEL CORPORATION (JP) 2012-08-16 US disclosed
EP-1524332-B1 SURFACE-TREATED STEEL SHEET EXCELLENT IN RESISTANCE TO WHITE RUST AND METHOD FOR PRODUCTION THEREOF JFE STEEL CORP (JP) 2011-09-14 EP disclosed
US-20060141230-A1 Highly corrosion-resistant surface-treated steel sheet and method for producing same JFE STEEL CORPORATION (JP) 2006-06-29 US disclosed
EP-1634932-A1 HIGHLY CORROSION-RESISTANT SURFACE-TREATED STEEL SHEET AND METHOD FOR PRODUCING SAME JFE Steel Corporation (JP) 2006-03-15 EP disclosed
EP-1629969-A1 SURFACE TREATED STEEL PLATE EXCELLENT IN CORROSION RESISTANCE, ELECTROCONDUCTIVITY AND APPEARANCE OF COATING FILM JFE Steel Corporation (JP) 2006-03-01 EP disclosed
US-20050147832-A1 Surface-treated steel sheet excellent in resistance to white rust and method for production thereof KANSAI PAINT CO., LTD. (JP) 2005-07-07 US disclosed
EP-1524332-A1 SURFACE-TREATED STEEL SHEET EXCELLENT IN RESISTANCE TO WHITE RUST AND METHOD FOR PRODUCTION THEREOF JFE Steel Corporation (JP) 2005-04-20 EP disclosed
US-6562474-B1 Coated steel sheet having excellent corrosion resistance and method for producing the same NKK CORPORATION (JP) 2003-05-13 US disclosed
US-20030072962-A1 Steel sheet having organic coating and method for manufacturing the same NKK CORPORATION (JP) 2003-04-17 US disclosed
EP-1291453-A1 ORGANIC COATING COVERED STEEL SHEET NKK CORPORATION (JP) 2003-03-12 EP disclosed
EP-1050603-A1 SURFACE TREATED STEEL SHEET HAVING EXCELLENT CORROSION RESISTANCE AND METHOD FOR PRODUCING THE SAME NKK CORPORATION (JP) 2000-11-08 EP disclosed
US-4728355-A RETARDING SENESCENCE IN SOYBEANS AND COTTON FMC CORPORATION (US) 1988-03-01 US disclosed