Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 8/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749524 | 0.91 | MET (0.43) | METRETKDRAXLEGFR | |
| SCHEMBL23749326 | 0.86 | MET (0.50) | METRETKDRAXLEGFR | |
| SCHEMBL23749332 | 0.85 | KDR (0.47) | METRETKDRAXLEGFR | |
| SCHEMBL22769707 | 0.85 | MET (0.51) | METRETKDRAXLEGFR | |
| SCHEMBL21750981 | 0.83 | KDR (0.61) | METRETKDRAXLEGFR | |
| SCHEMBL23749460 | 0.82 | MET (0.63) | METRETKDRAXLEGFR | |
| SCHEMBL23749485 | 0.82 | RET (0.51) | METRETKDRAXL | |
| SCHEMBL23749430 | 0.81 | RET (0.61) | METRETKDRAXLEGFR | |
| SCHEMBL21751027 | 0.81 | KDR (0.61) | METRETKDRAXLEGFR | |
| SCHEMBL23749317 | 0.80 | KDR (0.53) | METRETKDRAXLEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |