Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.58 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | RET | P07949 | 7/20 | 0.52 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749311 | 0.95 | KDR (0.53) | KDREGFRRETMETAXL | |
| SCHEMBL31441116 | 0.94 | KDR (0.64) | KDREGFRRETMETAXL | |
| SCHEMBL23749300 | 0.94 | KDR (0.64) | KDREGFRRETMETAXL | |
| SCHEMBL23749272 | 0.93 | KDR (0.54) | KDREGFRRETMETAXL | |
| SCHEMBL23749498 | 0.83 | MET (0.63) | KDREGFRRETMETAXL | |
| SCHEMBL21750981 | 0.82 | KDR (0.61) | KDREGFRRETMETAXL | |
| SCHEMBL22769707 | 0.81 | MET (0.51) | KDREGFRRETMETAXL | |
| SCHEMBL23749326 | 0.80 | MET (0.50) | KDREGFRRETMETAXL | |
| SCHEMBL21265615 | 0.79 | KDR (0.91) | KDREGFRRETMETAXL | |
| SCHEMBL23749404 | 0.79 | RET (0.51) | KDREGFRRETMETAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |