Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 9/20 | 0.55 |
| ▸ | KDR | P35968 | 8/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441123 | 1.00 | RET (0.55) | RETKDREHMT2EHMT1EGFR | |
| SCHEMBL23749286 | 0.93 | RET (0.62) | RETKDREGFRRAF1BRAF | |
| SCHEMBL22781910 | 0.87 | KDR (0.60) | RETKDREGFRRAF1BRAF | |
| SCHEMBL21751019 | 0.86 | RAF1 (0.56) | KDREGFRRAF1BRAF | |
| SCHEMBL30664567 | 0.86 | RAF1 (0.56) | KDREGFRRAF1BRAF | |
| SCHEMBL23749341 | 0.83 | KDR (0.61) | RETKDR | |
| SCHEMBL21265689 | 0.83 | RET (0.58) | RETKDREGFRRAF1BRAF | |
| SCHEMBL23749389 | 0.82 | RET (0.58) | RETKDREGFR | |
| SCHEMBL23770980 | 0.81 | RET (0.57) | RETKDREGFRRAF1BRAF | |
| SCHEMBL21246991 | 0.81 | RET (0.62) | RETKDREGFRRAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |