Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 6/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | MET | P08581 | 4/20 | 0.45 |
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | BRAF | P15056 | 2/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31441112 | 1.00 | AXL (0.59) | AXLRETKDREGFRMET | |
| SCHEMBL23749319 | 0.99 | AXL (0.58) | AXLRETKDREGFRMET | |
| SCHEMBL21265307 | 0.94 | AXL (0.68) | AXLRETKDREGFRMET | |
| SCHEMBL23749340 | 0.93 | AXL (0.60) | AXLRETKDREGFRMET | |
| SCHEMBL23749501 | 0.91 | RET (0.56) | AXLRETKDREGFRMET | |
| SCHEMBL23749350 | 0.91 | AXL (0.57) | AXLRETKDREGFRMET | |
| SCHEMBL23749499 | 0.91 | AXL (0.55) | AXLRETKDREGFRMET | |
| SCHEMBL23749330 | 0.90 | AXL (0.57) | AXLRETKDREGFRMET | |
| SCHEMBL23749577 | 0.90 | AXL (0.57) | AXLRETKDREGFRMET | |
| SCHEMBL23749358 | 0.89 | RET (0.57) | AXLRETKDREGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |