Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 10/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | RET | P07949 | 6/20 | 0.52 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749459 | 0.91 | MET (0.59) | METKDRRETAXL | |
| SCHEMBL23771068 | 0.91 | MET (0.55) | METKDRRETAXL | |
| SCHEMBL23749574 | 0.90 | KDR (0.67) | METKDRRETAXL | |
| SCHEMBL23749465 | 0.90 | KDR (0.61) | METKDRRETAXL | |
| SCHEMBL23749367 | 0.90 | MET (0.66) | METKDRRETAXL | |
| SCHEMBL24179445 | 0.90 | RET (0.54) | METKDRRETAXL | |
| SCHEMBL23771010 | 0.90 | RET (0.54) | METKDRRETAXL | |
| SCHEMBL23749534 | 0.89 | MET (0.57) | METKDRRETAXL | |
| SCHEMBL23749307 | 0.86 | KDR (0.54) | METKDRRETAXL | |
| SCHEMBL23749412 | 0.86 | MET (0.67) | METKDRRETAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |