SCHEMBL23750071

SCHEMBL23750071

CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCC=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCCCCN

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 6/20 0.56
▸ IL23R Q5VWK5 8/20 0.51
▸ KISS1R Q969F8 1/20 0.50
▸ C5AR1 P21730 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24991032 0.93 C5AR1 (0.51) MC4RC5AR1
SCHEMBL23750222 0.92 MC4R (0.45) MC4RIL23RKISS1RC5AR1
SCHEMBL18716889 0.92 MC4R (0.53) MC4RIL23RKISS1RC5AR1
SCHEMBL29420167 0.89 MC4R (0.64) MC4RKISS1R
SCHEMBL12057583 0.89 MC4R (0.64) MC4RKISS1R
SCHEMBL14523926 0.89 MC4R (0.51) MC4RIL23RKISS1RC5AR1
SCHEMBL14552580 0.88 MC4R (0.54) MC4RIL23RKISS1RC5AR1
SCHEMBL30464981 0.86 IL23R (0.60) MC4RIL23R
SCHEMBL30464995 0.86 IL23R (0.61) MC4RIL23RKISS1R
SCHEMBL29814670 0.86 IL23R (0.61) MC4RIL23RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 — — US disclosed
WO-2021158463-A1 DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2021-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R MC4R 4/4885IL23R 200/4885KISS1R 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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