SCHEMBL14552580

SCHEMBL14552580

CC(=O)N[C@@H](CCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C)CCO

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.54
▸ KISS1R Q969F8 4/20 0.53
▸ IL23R Q5VWK5 7/20 0.51
▸ TUBB4A P04350 2/20 0.50
▸ TUBB P07437 2/20 0.50
▸ TUBA3C P0DPH7 2/20 0.50
▸ TUBA1B P68363 2/20 0.50
▸ TUBA4A P68366 2/20 0.50
▸ TUBB4B P68371 2/20 0.50
▸ TUBB3 Q13509 2/20 0.50
▸ TUBB2A Q13885 2/20 0.50
▸ TUBB8 Q3ZCM7 2/20 0.50
▸ TUBA3E Q6PEY2 2/20 0.50
▸ TUBA1A Q71U36 2/20 0.50
▸ TUBA1C Q9BQE3 2/20 0.50
▸ TUBB6 Q9BUF5 2/20 0.50
▸ TUBB2B Q9BVA1 2/20 0.50
▸ TUBB1 Q9H4B7 2/20 0.50
▸ GHSR Q92847 1/20 0.49
▸ C5AR1 P21730 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14552701 0.93 MC4R (0.54) MC4RKISS1RIL23RTUBB4ATUBB
SCHEMBL12057583 0.90 MC4R (0.64) MC4RKISS1R
SCHEMBL29420167 0.90 MC4R (0.64) MC4RKISS1R
SCHEMBL14552127 0.88 MC4R (0.54) MC4RKISS1RIL23R
SCHEMBL30464982 0.88 IL23R (0.59) MC4RKISS1RIL23RGHSR
SCHEMBL30464993 0.88 IL23R (0.58) MC4RKISS1RIL23R
SCHEMBL23750071 0.88 MC4R (0.56) MC4RKISS1RIL23RC5AR1
SCHEMBL29861838 0.87 KISS1R (0.56) MC4RKISS1R
SCHEMBL12094776 0.86 MC4R (0.54) MC4RKISS1RIL23RTUBB4ATUBB
SCHEMBL12094797 0.86 MC4R (0.58) MC4RKISS1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R MC4R 1/4885KISS1R 139/4885IL23R 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback