Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 6/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.47 |
| ▸ | NPY1R | P25929 | 4/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23750222 | 0.90 | MC4R (0.45) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30548763 | 0.88 | NPY4R (0.55) | APLNRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL24919552 | 0.88 | NPY4R (0.57) | APLNRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10168278 | 0.88 | APLNR (0.49) | APLNRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10168616 | 0.88 | APLNR (0.49) | APLNRNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL23750209 | 0.87 | C5AR1 (0.47) | APLNRC5AR1CHRNA1CHRNGCHRNB1 | |
| SCHEMBL23750092 | 0.87 | CHRNA1 (0.47) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10168808 | 0.86 | APLNR (0.55) | APLNRC5AR1 | |
| SCHEMBL10168706 | 0.84 | APLNR (0.54) | APLNRC5AR1 | |
| SCHEMBL10168588 | 0.84 | APLNR (0.54) | APLNRC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158463-A1 | DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES | PALATIN TECHNOLOGIES, INC. (US) | 2021-08-12 | — | — | WO | disclosed |