SCHEMBL237516

SCHEMBL237516

CC(C)(C)c1ccc(-c2ccccc2OC(=O)Oc2ccccc2-c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.50
MAPT P10636 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
BACE1 P56817 1/20 0.42
MEN1 O00255 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD11B1 P28845 1/20 0.41
HSD17B3 P37058 1/20 0.41
RORB Q92753 1/20 0.41
FABP3 P05413 2/20 0.40
S1PR1 P21453 1/20 0.40
FABP7 O15540 1/20 0.40
FABP5 Q01469 1/20 0.40
EGFR P00533 1/20 0.40
CHRM3 P20309 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HIF1A Q16665 1/20 0.40
KIF11 P52732 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17720804 0.90 MAPT (0.55) NPSR1MAPTL3MBTL1TDP1BACE1
SCHEMBL29949950 0.89 NPSR1 (0.49) NPSR1MAPTL3MBTL1TDP1BACE1
SCHEMBL237517 0.89 NPSR1 (0.49) NPSR1MAPTL3MBTL1TDP1BACE1
SCHEMBL235936 0.87 ALDH1A1 (0.44) NPSR1MAPTL3MBTL1TDP1BACE1
SCHEMBL237543 0.87 FABP3 (0.43) NPSR1MAPTL3MBTL1TDP1BACE1
SCHEMBL236822 0.80 FABP3 (0.53) L3MBTL1TDP1RAB9AFABP3FABP7
SCHEMBL1638833 0.80 FABP3 (0.56) L3MBTL1TDP1RAB9AFABP3FABP7
SCHEMBL8059089 0.79 ESR2 (0.47) MAPTL3MBTL1TDP1BACE1MEN1
SCHEMBL10145033 0.79 ALDH1A1 (0.52) NPSR1MAPTMEN1KMT2AALDH1A1
SCHEMBL8065693 0.78 BACE1 (0.54) NPSR1MAPTL3MBTL1TDP1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114599706-B Process for preparing polyester carbonates 科思创德国股份有限公司 2025-02-18 CN claimed
EP-4055080-A1 PROCESS FOR PREPARING POLYESTER CARBONATES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-09-14 EP claimed
CN-114599706-A Method for producing polyester carbonates 科思创知识产权两合公司 2022-06-07 CN claimed
EP-2655384-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
EP-2655383-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
US-8563638-B2 Oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-10-22 US claimed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US claimed
US-20120171460-A1 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
US-20120172500-A1 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
WO-2012088406-A2 OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
WO-2012088435-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
EP-4526369-A1 POLYSILOXANE-POLYCARBONATE BLOCK CO-CONDENSATES FORMED FROM SPECIFICALLY TERMINATED SILOXANE BLOCKS Covestro Deutschland AG (DE) 2025-03-26 EP disclosed
CN-114599706-B Process for preparing polyester carbonates 科思创德国股份有限公司 2025-02-18 CN disclosed
EP-4493388-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-01-22 EP disclosed
CN-119213054-A Polycarbonate cocondensates having phenolic structural units 科思创德国股份有限公司 2024-12-27 CN disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed