SCHEMBL23752182

SCHEMBL23752182

O=P(O)(O)C(O)(Cc1cccc(-c2cccc3c2oc2ccccc23)c1)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 5/20 1.00
ALOX5 P09917 2/20 0.50
FDPS P14324 5/20 0.47
CDC14B O60729 3/20 0.45
CDC14A Q9UNH5 3/20 0.45
PTGES2 Q9H7Z7 1/20 0.41
PRKDC P78527 2/20 0.39
BTN3A1 O00481 1/20 0.39
PDE3A Q14432 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12257822 0.83 GGPS1 (0.71) GGPS1FDPSCDC14BCDC14ABTN3A1
SCHEMBL23621465 0.80 GGPS1 (0.67) GGPS1ALOX5CDC14BCDC14APTGES2
SCHEMBL13458846 0.80 GGPS1 (0.78) GGPS1FDPSBTN3A1PDE3A
SCHEMBL13986662 0.76 GGPS1 (0.61) GGPS1ALOX5CDC14BCDC14APTGES2
SCHEMBL12996512 0.75 ALOX5 (0.71) GGPS1ALOX5PTGES2PRKDCPRMT5
SCHEMBL13431339 0.74 GGPS1 (1.00) GGPS1FDPSBTN3A1PDE3A
SCHEMBL13986663 0.74 GGPS1 (0.58) GGPS1ALOX5PTGES2PRKDCPRMT5
SCHEMBL12996525 0.73 ALOX5 (0.69) GGPS1ALOX5PTGES2PRKDCPRMT5
SCHEMBL15855421 0.73 ALOX5 (0.69) GGPS1ALOX5PTGES2PRKDCPRMT5
SCHEMBL431478 0.72 ALOX5 (0.67) GGPS1ALOX5PTGES2PRKDCPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed