Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.75 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | FPR2 | P25090 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13373356 | 0.86 | ROCK2 (0.74) | ROCK2ROCK1 | |
| SCHEMBL4606056 | 0.80 | EPHX1 (0.81) | ROCK2ROCK1NPC1RAB9ACNR1 | |
| SCHEMBL9720272 | 0.79 | ROCK2 (0.71) | ROCK2ROCK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4885892 | 0.78 | ROCK2 (0.62) | ROCK2ROCK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6055223 | 0.77 | EPHX2 (0.62) | ROCK2NPC1RAB9ASMN1; SMN2HDAC1 | |
| SCHEMBL6032606 | 0.75 | EPHX1 (0.85) | NPC1RAB9ACNR1SMN1; SMN2EPHX1 | |
| SCHEMBL15146106 | 0.75 | ROCK2 (1.00) | ROCK2ROCK1NPC1RAB9APRMT3 | |
| SCHEMBL31061022 | 0.75 | ROCK2 (1.00) | ROCK2ROCK1NPC1RAB9APRMT3 | |
| SCHEMBL15145533 | 0.75 | ROCK2 (0.83) | ROCK2ROCK1NPC1RAB9ACNR1 | |
| SCHEMBL23431947 | 0.74 | NAMPT (0.77) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106114-A1 | IDENTIFICATION OF HUMAN T2R RECEPTORS AND THE USE THEREOF TO IDENTIFY INHIBITORS (BLOCKERS) OF BITTER TASTE | SENOMYX, INC. (US) | 2011-09-01 | — | — | WO | disclosed |