⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704711 | 0.69 | — | — | |
| SCHEMBL23704479 | 0.69 | — | — | |
| SCHEMBL28859570 | 0.67 | — | — | |
| Ethylene SCHEMBL6344825 | 0.62 | — | — | |
| SCHEMBL6549570 | 0.59 | — | — | |
| SCHEMBL672452 | 0.59 | — | — | |
| SCHEMBL28739386 | 0.59 | LMNA (0.43) | — | |
| SCHEMBL1033028 | 0.57 | — | — | |
| SCHEMBL14491253 | 0.57 | — | — | |
| SCHEMBL13467407 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150935-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-18 | — | — | US | disclosed |
| EP-4103551-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | The Regents of the University of California (US) | 2022-12-21 | — | — | EP | disclosed |
| WO-2021163493-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING CALCIUM ION HOMEOSTASIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-19 | — | — | WO | disclosed |