⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23559104 | 0.86 | — | — | |
| SCHEMBL84828 | 0.80 | — | — | |
| SCHEMBL1607123 | 0.75 | — | — | |
| SCHEMBL21999980 | 0.70 | — | — | |
| SCHEMBL2840541 | 0.70 | — | — | |
| SCHEMBL17086160 | 0.70 | — | — | |
| SCHEMBL18469867 | 0.70 | — | — | |
| SCHEMBL6235734 | 0.67 | — | — | |
| SCHEMBL27473081 | 0.67 | HSD17B10 (0.44) | — | |
| SCHEMBL27728325 | 0.66 | RAB9A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11091464-B2 | Pyridazinone compounds and uses thereof | EDGEWISE THERAPEUTICS, INC. (US) | 2021-08-17 | — | — | US | disclosed |