SCHEMBL23758680

SCHEMBL23758680

c1ccc(-c2cccc(-c3c4ccccc4c(-c4ccc5c(c4)Oc4cccc6c(-c7ccc(-c8ccc(-c9c%10ccccc%10c(-c%10ccc%11c(c%10)Oc%10cccc%12cccc-%11c%10%12)c%10ccccc9%10)cc8)cc7)ccc-5c46)c4ccccc34)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ATM Q13315 1/20 0.48
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
TYMS P04818 1/20 0.35
GPR84 Q9NQS5 2/20 0.33
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
TNF P01375 1/20 0.30
ENPP1 P22413 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22971975 0.94 MAPK1 (0.54) MAPK1KDM4EATMCA12CA1
SCHEMBL23109581 0.94 MAPK1 (0.54) MAPK1KDM4EATMCA12CA1
SCHEMBL23758678 0.93 KDM4E (0.44) MAPK1KDM4EATMCA12CA1
SCHEMBL16558533 0.93 MAPK1 (0.54) MAPK1KDM4EATMCA12CA1
SCHEMBL22969549 0.93 MAPK1 (0.55) MAPK1KDM4EATMCA12CA1
SCHEMBL22969551 0.93 MAPK1 (0.55) MAPK1KDM4EATMCA12CA1
SCHEMBL16558460 0.92 MAPK1 (0.55) MAPK1KDM4EATMCA12CA1
SCHEMBL22971964 0.92 MAPK1 (0.57) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376420 0.90 MAPK1 (0.53) MAPK1KDM4EATMCA12CA1
SCHEMBL16376374 0.90 MAPK1 (0.53) MAPK1KDM4EATMCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11839148-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 US disclosed
US-11094886-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed