SCHEMBL16376374

SCHEMBL16376374

c1ccc(-c2ccc(-c3c4ccccc4c(-c4ccc5c(c4)Oc4cccc6cccc-5c46)c4ccccc34)c3ccccc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 5/20 0.53
KDM4E B2RXH2 5/20 0.53
ATM Q13315 3/20 0.53
TYMS P04818 1/20 0.39
GPR84 Q9NQS5 3/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
TNF P01375 1/20 0.33
ALDH1A1 P00352 5/20 0.33
TSHR P16473 4/20 0.33
HSD17B10 Q99714 4/20 0.33
HPGD P15428 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
CASP1 P29466 2/20 0.33
HIF1A Q16665 2/20 0.33
TP53 P04637 2/20 0.33
CASP7 P55210 1/20 0.33
MEN1 O00255 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16376420 1.00 MAPK1 (0.53) MAPK1KDM4EATMTYMSGPR84
SCHEMBL22971965 0.95 MAPK1 (0.53) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376422 0.95 MAPK1 (0.53) MAPK1KDM4EATMTYMSGPR84
SCHEMBL22971964 0.93 MAPK1 (0.57) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376372 0.93 KDM4E (0.43) MAPK1KDM4EATMGPR84CA12
SCHEMBL22969549 0.92 MAPK1 (0.55) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376403 0.92 MAPK1 (0.55) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376363 0.92 MAPK1 (0.55) MAPK1KDM4EATMTYMSGPR84
SCHEMBL16376377 0.91 MAPK1 (0.51) MAPK1KDM4EATMTYMSGPR84
SCHEMBL23109581 0.91 MAPK1 (0.54) MAPK1KDM4EATMTYMSGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-01-18 US disclosed
US-11839148-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-12-05 US disclosed
US-20230209996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209996-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-20230209998-A1 ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed
US-11552259-B1 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-01-10 US disclosed
US-20220393113-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-08 US disclosed
US-11094886-B2 Organic electroluminescent element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20210083193-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-03-18 US disclosed
US-10256416-B2 Compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-09 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed
US-20150001479-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240023436-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE EED, EML4, ESR1 MAPK1 2256/4885KDM4E 494/4885ATM 2500/4885
US-10256416-B2 Compound and organic light-emitting device including the same ALDH1A2, AOX1, OR10J3 MAPK1 617/4885KDM4E 2779/4885ATM 3093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.