Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103742 | 0.90 | TYK2 (0.49) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL24984727 | 0.83 | TYK2 (0.48) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL23759204 | 0.82 | TYK2 (0.63) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL21887360 | 0.81 | TYK2 (0.52) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL21887357 | 0.81 | TYK2 (0.58) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL22103745 | 0.77 | TYK2 (0.63) | TYK2JAK1STAT3 | |
| SCHEMBL22343290 | 0.77 | TYK2 (0.65) | TYK2PDE4DJAK1 | |
| SCHEMBL22324403 | 0.76 | TYK2 (0.69) | TYK2PDE4DJAK1 | |
| SCHEMBL24961646 | 0.75 | TYK2 (0.51) | TYK2PDE4DJAK1STAT3 | |
| SCHEMBL24961733 | 0.75 | TYK2 (0.57) | TYK2PDE4DJAK1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162944-A1 | SUBSTITUTED 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2021-08-19 | — | — | WO | disclosed |