Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22103742 | 0.93 | TYK2 (0.49) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL24961733 | 0.84 | TYK2 (0.57) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL24961646 | 0.84 | TYK2 (0.51) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL23759209 | 0.83 | TYK2 (0.50) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL23759204 | 0.83 | TYK2 (0.63) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL22103738 | 0.82 | TYK2 (0.58) | TYK2STAT3PDE4D | |
| SCHEMBL24224245 | 0.81 | TYK2 (0.49) | TYK2STAT3PDE4D | |
| SCHEMBL21887360 | 0.77 | TYK2 (0.52) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL21887357 | 0.77 | TYK2 (0.58) | TYK2STAT3JAK1PDE4D | |
| SCHEMBL22103745 | 0.75 | TYK2 (0.63) | TYK2STAT3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3894412-B1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE DERIVATIVES | LILLY CO ELI (US) | 2023-02-08 | — | — | EP | disclosed |