Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.85 |
| ▸ | KDR | P35968 | 5/20 | 0.85 |
| ▸ | AXL | P30530 | 3/20 | 0.85 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.85 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.85 |
| ▸ | MERTK | Q12866 | 1/20 | 0.57 |
| ▸ | MST1R | Q04912 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20248763 | 0.94 | MET (0.86) | METKDRAXLPDGFRBPDGFRA | |
| Tas-115 SCHEMBL29853531 | 0.92 | MET (1.00) | METKDRAXLPDGFRBPDGFRA | |
| Tas-115 SCHEMBL1132590 | 0.92 | MET (1.00) | METKDRAXLPDGFRBPDGFRA | |
| Tas-115 SCHEMBL16782348 | 0.90 | MET (0.94) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL28522290 | 0.89 | MET (0.74) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL29217448 | 0.86 | MET (0.65) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL23677959 | 0.85 | MET (0.87) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL1132173 | 0.85 | MET (0.86) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL1132734 | 0.85 | MET (0.88) | METKDRAXLPDGFRBPDGFRA | |
| SCHEMBL21863364 | 0.84 | MET (0.76) | METKDRAXLPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162097-A1 | ANALOGOUS SUBSTANCES OF ACYL THIOUREA COMPOUND | 大鵬薬品工業株式会社 | 2021-08-19 | — | — | WO | disclosed |
| WO-2021162096-A1 | METHOD FOR PRODUCING ACYLTHIOUREA COMPOUND | 大鵬薬品工業株式会社 | 2021-08-19 | — | — | WO | disclosed |