SCHEMBL23764170

SCHEMBL23764170

Cc1ccc(N(c2cccnc2)c2cccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.39
CYP11B2 P19099 2/20 0.39
FYN P06241 1/20 0.37
MAP2K4 P45985 1/20 0.36
CKS1B P61024 1/20 0.35
SKP2 Q13309 1/20 0.35
BTK Q06187 1/20 0.35
CYP17A1 P05093 2/20 0.34
MAPT P10636 3/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP1A2 P05177 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16483925 0.92 CYP11B1 (0.43) CYP11B1CYP11B2FYNCKS1BSKP2
SCHEMBL17012371 0.92 CYP11B1 (0.45) CYP11B1CYP11B2FYNMAPTMAPK1
SCHEMBL16484718 0.92 CYP11B1 (0.45) CYP11B1CYP11B2FYNMAPTMAPK1
SCHEMBL16484087 0.91 CYP11B1 (0.40) CYP11B1CYP11B2FYNCYP17A1MAPT
SCHEMBL23764150 0.91 CYP11B1 (0.36) CYP11B1CYP11B2FYNMAP2K4CKS1B
SCHEMBL16484067 0.90 CYP11B1 (0.42) CYP11B1CYP11B2FYNCYP17A1MAPT
SCHEMBL16483903 0.90 CYP11B1 (0.41) CYP11B1CYP11B2FYNCYP17A1MAPT
SCHEMBL23764168 0.88 KDM4E (0.37) MAPTMAPK1KDM4ECYP1A2SMN1; SMN2
SCHEMBL16484653 0.88 TNF (0.42) CYP11B1CYP11B2FYNCYP17A1MAPT
SCHEMBL16484746 0.87 CYP11B1 (0.44) CYP11B1CYP11B2FYNCYP17A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed