SCHEMBL23764168

SCHEMBL23764168

Cc1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c(cccc35)-c3ccccc3-4)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.37
MAPT P10636 2/20 0.37
PABPC1 P11940 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
ALDH1A1 P00352 5/20 0.35
HPGD P15428 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP1 P29466 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PTPRC P08575 1/20 0.35
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CRHR1 P34998 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485045 0.95 MAPT (0.36) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL23764362 0.92 HPRT1 (0.35) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL9888959 0.91 CRHBP (0.42) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL23764421 0.90 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10CRHR1
SCHEMBL23764153 0.90 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10CRHR1
SCHEMBL20016927 0.89 ALDH1A1 (0.37) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL23764110 0.89 KDM4E (0.40) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL402974 0.88 BRD4 (0.35) KDM4EMAPTALDH1A1HPGDL3MBTL1
SCHEMBL23764501 0.88 KDM4E (0.38) KDM4EMAPTPABPC1SMN1; SMN2CRHBP
SCHEMBL23764170 0.88 CYP11B1 (0.39) KDM4EMAPTSMN1; SMN2MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed