Triethylene Glycol

Triethylene Glycol

SCHEMBL2376419

C=CC(=O)Oc1ccccc1.OCCOCCOCCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.53
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
TP53 P04637 2/20 0.44
HIF1A Q16665 2/20 0.44
RECQL P46063 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KMT2A Q03164 4/20 0.40
PTK2B Q14289 1/20 0.40
PDE6D O43924 1/20 0.40
GAA P10253 1/20 0.39
THRA P10827 1/20 0.38
MEN1 O00255 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TGM2 P21980 1/20 0.37
AKT1 P31749 1/20 0.36
TEAD1 P28347 1/20 0.36
TEAD3 Q99594 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL9738612 0.98 THRB (0.54) THRBALDH1A1TSHRTP53HIF1A
Triethylene Glycol SCHEMBL7896473 0.93 THRB (0.47) THRBALDH1A1TSHRTP53HIF1A
Tetraethylene Glycol SCHEMBL18092769 0.93 THRB (0.47) THRBALDH1A1TSHRTP53HIF1A
Diethylene Glycol Monoethyl Ether SCHEMBL1508669 0.93 THRB (0.47) THRBALDH1A1TSHRTP53HIF1A
Di(Hydroxyethyl)Ether SCHEMBL2345984 0.91 THRB (0.48) THRBALDH1A1TSHRTP53HIF1A
Ethylene Glycol SCHEMBL2694080 0.88 THRB (0.56) THRBALDH1A1TSHRRECQLHSD17B10
Di(Hydroxyethyl)Ether SCHEMBL11053211 0.87 THRB (0.44) THRBALDH1A1TSHRRECQLKMT2A
SCHEMBL7194597 0.87 THRB (0.66) THRBALDH1A1TSHRTP53HIF1A
Triethylene Glycol SCHEMBL1614163 0.86 THRB (0.49) THRBALDH1A1TSHRTP53HIF1A
Tetraethylene Glycol SCHEMBL183504 0.86 THRB (0.49) THRBALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110218289-A1 MIXTURE COMPOSITION CONTAINING COPOLYMERS BASED ON UNSATURATED CARBOXYLIC ACID AND ALKENYL ETHER DERIVATIVES AND COPOLYMERS AND TERPOLYMERS CONTAINING SULFO GROUPS AND USE THEREOF MAIER MARKUS 2011-09-08 US disclosed
US-20070287817-A1 Mixture Composition Containing Unsaturated Carboxylic Acid and Alkene Ether Derivative Based Copolymers and Copolymers and Terpolymers Containing Sulfo Groups and Use Thereof CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2007-12-13 US disclosed