Sugi Predict

Sugi Predict / Compounds / SCHEMBL23764463

SCHEMBL23764463

SCHEMBL23764463

Cc1ccc(-c2ccc(N(c3ccccc3)c3cccc(-c4ccc5c6c(cccc46)-c4c-5c(-c5ccccc5)c5ccccc5c4-c4ccccc4)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ENPP1 P22413 1/20 0.33
▸ ACHE P22303 1/20 0.32
▸ CRHR1 P34998 1/20 0.31
▸ HPRT1 P00492 1/20 0.31
▸ PTGS2 P35354 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764421 0.98 KDM4E (0.32) ENPP1ACHECRHR1KDM4ENPSR1
SCHEMBL23764153 0.98 KDM4E (0.32) ENPP1ACHECRHR1KDM4ENPSR1
SCHEMBL23764347 0.95 DHODH (0.33) ENPP1ACHECRHR1HPRT1
SCHEMBL16484487 0.93 ENPP1 (0.38) ENPP1ACHECRHR1HPRT1KDM4E
SCHEMBL13085095 0.90 MCL1 (0.32) ENPP1KDM4EHSD17B10
SCHEMBL23764464 0.89 MCL1 (0.35) ENPP1CRHR1KDM4E
SCHEMBL23764074 0.89 HTT (0.33) ENPP1CRHR1KDM4ENPSR1HSD17B10
SCHEMBL23764449 0.89 PADI4 (0.35) HSD17B10
SCHEMBL23764383 0.89 TAAR1 (0.35) NPSR1
SCHEMBL23764150 0.88 CYP11B1 (0.36) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 — — EP disclosed