SCHEMBL23764464

SCHEMBL23764464

Cc1ccccc1-c1ccc(N(c2ccccc2)c2cccc(-c3ccc4c5c(cccc35)-c3c-4c(-c4ccccc4)c4ccccc4c3-c3ccccc3)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.35
KDM4E B2RXH2 1/20 0.35
HTR7 P34969 3/20 0.34
MAPT P10636 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
PTPN1 P18031 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
TRPA1 O75762 1/20 0.32
CTSD P07339 1/20 0.32
BACE1 P56817 1/20 0.32
ESR2 Q92731 1/20 0.32
RPA1 P27694 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23764501 0.90 KDM4E (0.38) MCL1KDM4EHTR7MAPTNR1H4
SCHEMBL23764463 0.89 ENPP1 (0.33) KDM4EENPP1CRHR1
SCHEMBL23764421 0.89 KDM4E (0.32) KDM4EALDH1A1ENPP1CRHR1
SCHEMBL23764153 0.89 KDM4E (0.32) KDM4EALDH1A1ENPP1CRHR1
SCHEMBL13085095 0.89 MCL1 (0.32) MCL1KDM4EMAPTALDH1A1CYP1A2
SCHEMBL12032283 0.89 ENPP1 (0.35) KDM4EMAPTALDH1A1CYP1A2CYP3A4
SCHEMBL23764074 0.88 HTT (0.33) KDM4EMAPTALDH1A1TSHRMAPK1
SCHEMBL12032229 0.88 ENPP1 (0.35) KDM4EMAPTALDH1A1CYP1A2CYP3A4
SCHEMBL4078983 0.88 ENPP1 (0.35) KDM4EMAPTALDH1A1CYP1A2CYP3A4
SCHEMBL16484487 0.87 ENPP1 (0.38) KDM4EMAPTALDH1A1ENPP1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2907803-B1 FLUORANTHENE DERIVATIVE, LUMINESCENT ELEMENT MATERIAL CONTAINING SAME, AND LUMINESCENT ELEMENT TORAY INDUSTRIES (JP) 2021-08-18 EP disclosed