Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14617832 | 0.87 | CA14 (0.34) | CA14HDAC6SLC6A2SLC6A4 | |
| SCHEMBL18260865 | 0.78 | KDM4E (0.36) | HDAC6 | |
| SCHEMBL18260867 | 0.78 | KDM4E (0.36) | HDAC6 | |
| SCHEMBL18285886 | 0.77 | CA14 (0.43) | CA14HDAC6 | |
| SCHEMBL23170318 | 0.77 | HDAC6 (0.39) | CA14HDAC6SLC6A4 | |
| SCHEMBL23857521 | 0.77 | CA14 (0.45) | CA14HDAC6 | |
| SCHEMBL18759031 | 0.77 | CA14 (0.42) | CA14HDAC6 | |
| SCHEMBL19339624 | 0.75 | CA14 (0.38) | CA14HDAC6 | |
| SCHEMBL20783203 | 0.75 | CA14 (0.41) | CA14HDAC6SLC6A2SLC6A4 | |
| SCHEMBL20365669 | 0.75 | MLYCD (0.44) | CA14HDAC6SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161109-A1 | PREPARATION OF A P2X3 ANTAGONIST | BELLUS HEALTH COUGH INC. (CA) | 2021-08-19 | — | — | WO | disclosed |