Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764643 | 0.88 | CHRM5 (0.56) | CHRM5 | |
| SCHEMBL23764713 | 0.86 | CHRM5 (0.53) | CHRM5 | |
| SCHEMBL23764618 | 0.84 | CHRM5 (0.51) | CHRM5 | |
| SCHEMBL23764661 | 0.80 | CHRM5 (0.67) | CHRM5 | |
| SCHEMBL23764621 | 0.80 | CHRM5 (0.43) | CHRM5 | |
| SCHEMBL23764670 | 0.79 | CHRM5 (0.55) | CHRM5 | |
| SCHEMBL23764645 | 0.79 | CHRM5 (0.54) | CHRM5 | |
| SCHEMBL23764704 | 0.79 | CHRM5 (0.55) | CHRM5 | |
| SCHEMBL23764689 | 0.78 | CHRM5 (0.56) | CHRM5 | |
| SCHEMBL23764647 | 0.75 | PARK7 (0.51) | CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162650-A1 | 5-FLUORO/5-TRIFLUOROMETHOXY-1H-INDOLE-2,3-DIONE 3-(4-PHENYLTHIOSEMICARBAZONE) DERIVATIVES AS INTERLEUKIN 1 (IL-1) ANTAGONISTS AND ANTI-PYRETIC AND/OR ANTI-INFLAMMATORY AGENTS FOR USE IN TREATING E.G. BEHÇET'S DISEASE | ISTANBUL UNIVERSITESI (TR) | 2021-08-19 | — | — | WO | disclosed |