Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23982914 | 0.85 | GAA (0.50) | ALDH1A1GAAHDAC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL27622843 | 0.81 | SLC6A2 (0.50) | POLBKMT2ASMN1; SMN2LMNAFAAH | |
| SCHEMBL22643526 | 0.80 | GAA (0.50) | ALDH1A1GAAHDAC1RAB9AKDM4E | |
| SCHEMBL14290045 | 0.80 | ALDH1A1 (0.54) | ALDH1A1GAAHDAC1RAB9AKDM4E | |
| SCHEMBL18530076 | 0.77 | ALDH1A1 (0.52) | ALDH1A1GAAHDAC1POLBRAB9A | |
| SCHEMBL24451230 | 0.77 | ALDH1A1 (0.55) | ALDH1A1GAAHDAC1POLBRAB9A | |
| SCHEMBL12468984 | 0.77 | ALDH1A1 (0.53) | ALDH1A1GAAHDAC1METKMT2A | |
| SCHEMBL10209096 | 0.77 | SLC6A2 (0.49) | GAAHDAC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL13664692 | 0.76 | EPHX1 (0.53) | ALDH1A1GAARAB9AKDM4ENPC1 | |
| SCHEMBL20096044 | 0.75 | ALDH1A1 (0.52) | ALDH1A1GAAHDAC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163629-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-08-19 | — | — | WO | disclosed |