Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23764913 | 0.81 | ALDH1A1 (0.41) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL23764878 | 0.79 | ALDH1A1 (0.39) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL21575564 | 0.76 | TDP1 (0.58) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL23764890 | 0.74 | ALDH1A1 (0.35) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL23774660 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HIF1AMEN1KMT2AMAPT | |
| SCHEMBL23764900 | 0.68 | ALDH1A1 (0.43) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL23764906 | 0.68 | ALDH1A1 (0.40) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL25061691 | 0.67 | ALDH1A1 (0.46) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL29381342 | 0.65 | ALDH1A1 (0.79) | HPGDALDH1A1CYP3A4TDP1HIF1A | |
| SCHEMBL311267 | 0.65 | ALDH1A1 (0.79) | HPGDALDH1A1CYP3A4TDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865544-A1 | FLUORESCENT RHODAMINE DYES WITH ENHANCED CELL PERMEABILITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-08-18 | — | — | EP | disclosed |