Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 18/20 | 0.58 |
| ▸ | CNR1 | P21554 | 8/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.58 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.58 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.58 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.58 |
| ▸ | TRPV5 | Q9NQA5 | 1/20 | 0.58 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.58 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.51 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23765328 | 0.95 | CNR2 (0.59) | CNR2CNR1TRPM8GPR55TRPA1 | |
| SCHEMBL25268322 | 0.94 | CNR2 (0.61) | CNR2CNR1TRPM8GPR55ABHD12 | |
| SCHEMBL22946285 | 0.94 | CNR2 (0.61) | CNR2CNR1TRPM8GPR55ABHD12 | |
| SCHEMBL23765260 | 0.94 | CNR2 (0.61) | CNR2CNR1TRPM8GPR55ABHD12 | |
| SCHEMBL25258533 | 0.85 | CNR2 (0.66) | CNR2CNR1TRPM8GPR55ABHD12 | |
| SCHEMBL25258530 | 0.85 | CNR2 (0.66) | CNR2CNR1TRPM8GPR55ABHD12 | |
| SCHEMBL23765210 | 0.85 | CNR1 (0.64) | CNR2CNR1 | |
| SCHEMBL19472305 | 0.84 | CNR2 (0.70) | CNR2CNR1TRPM8GPR55TRPA1 | |
| SCHEMBL19472298 | 0.82 | CNR2 (0.67) | CNR2CNR1TRPM8GPR55TRPA1 | |
| SCHEMBL25269138 | 0.82 | CNR2 (0.40) | CNR2CNR1TRPM8GPR55TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230375561-A1 | METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES | KADDURAH DAOUK RIMA F (US) | 2023-11-23 | — | — | US | disclosed |
| US-20230375561-A1 | METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES | KADDURAH DAOUK RIMA F (US) | 2023-11-23 | — | — | US | disclosed |
| WO-2021163023-A1 | STABLE FORMULATIONS OF DRONABINOL | TRYAGx Labs Inc. (US) | 2021-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230375561-A1 | METHODS FOR IDENTIFICATION, STRATIFICATION, AND TREATMENT OF CNS DISEASES | SLC25A20, CPT2, NDUFAB1 | CNR2 91/4885CNR1 106/4885TRPM8 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.