NDUFAB1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFAB1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
The Effects of Coenzyme A Combined With Abiraterone on Patients With CRPC	PHASE1/PHASE2	UNKNOWN
Acetylcarnitine and Insulin Sensitivity	PHASE2	COMPLETED
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Metabolic Cofactor Supplementation in Alzheimer's Disease (AD) and Parkinson's Disease (PD) Patients	PHASE2	COMPLETED
Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis	PHASE2	UNKNOWN
Deoxynucleosides Pyrimidines as Treatment for Mitochondrial Depletion Syndrome	PHASE2	RECRUITING
Nicotinamide Riboside in LVAD Recipients	EARLY_PHASE1	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Diagnostic Odyssey Survey 2	nan	COMPLETED
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Human Mitochondrial Stress-driven Obesity Resistance	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Relationship Between Mitochondrial Dysfunction and Fatique in Cancer Patients Following External Beam Radiation Therapy	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis	nan	UNKNOWN
Nutritional Therapy of the Deficits of Oxidation Mitochondrial of the Fatty Acids	nan	COMPLETED
Fatty Acid Oxidation Defects and Insulin Sensitivity	nan	COMPLETED
Mitochondrial Dysfunction in Diabetes	nan	COMPLETED
Fasting Tolerance in MCADD-infants	nan	UNKNOWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Lifestyle Intervention in Preparation for Pregnancy (LIPP)	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NDUFAB1 binder may also engage these)

Protein	Name	Similarity
Q0MQC2	—	1.000	Q0MQC2 →
Q0MQC1	—	1.000	Q0MQC1 →
Q0MQC3	—	1.000	Q0MQC3 →
Q9CR21	—	0.997	Q9CR21 →
P52505	—	0.996	P52505 →
Q94519	—	0.993	Q94519 →
B5DKJ8	—	0.984	B5DKJ8 →
P00258	—	0.983	P00258 →
B4H303	—	0.983	B4H303 →
B4M375	—	0.983	B4M375 →
B4JWR9	—	0.983	B4JWR9 →
Q9FGJ4	—	0.982	Q9FGJ4 →
B4R3T1	—	0.982	B4R3T1 →
P25702	—	0.981	P25702 →
Q05B87	—	0.981	Q05B87 →
B3MRT7	—	0.981	B3MRT7 →
Q8N5N7	—	0.980	Q8N5N7 →
Q16595	—	0.980	Q16595 →
B4PZ52	—	0.979	B4PZ52 →
O35943	—	0.979	O35943 →
O76454	—	0.979	O76454 →
Q8VDT9	—	0.979	Q8VDT9 →
P24483	—	0.978	P24483 →
P02902	—	0.978	P02902 →
Q5REH5	—	0.978	Q5REH5 →
Q54E22	—	0.978	Q54E22 →
B4IMF6	—	0.978	B4IMF6 →
Q6P4F2	—	0.978	Q6P4F2 →
Q9M0V0	—	0.978	Q9M0V0 →
A1L1P7	—	0.977	A1L1P7 →