Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ESRRA | P11474 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23765855 | 0.92 | ESR1 (0.62) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23765686 | 0.86 | ESR1 (0.60) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL26462718 | 0.86 | ESR1 (0.57) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23424242 | 0.85 | ESR1 (0.59) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23424239 | 0.84 | ESR1 (0.58) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23765680 | 0.84 | ESR1 (0.59) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23424229 | 0.84 | ESR1 (0.75) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL23424204 | 0.83 | ESR1 (0.55) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL25629970 | 0.83 | ESR1 (0.53) | ESR1ESR2HDAC3HDAC6PGR | |
| SCHEMBL21077470 | 0.83 | ESR1 (0.67) | ESR1ESR2HDAC3HDAC6PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | KI PHARMACEUTICALS, LLC | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | CYP19A1, PGR, CYP21A2 | ESR1 9/4885ESR2 13/4885HDAC3 1758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.