Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595745 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL21017164 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL22570595 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL24178064 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL19632208 | 0.97 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CXCR4ACHEKMT2A | |
| SCHEMBL25069814 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL21993471 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL22489565 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL15889098 | 0.97 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2CXCR4ACHEEPHX1 | |
| SCHEMBL19198191 | 0.97 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2CXCR4ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3132247-B1 | METHODS, KITS AND APPARATUS FOR EXPANDING A POPULATION OF CELLS | JUNO THERAPEUTICS GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |