SCHEMBL23765706

SCHEMBL23765706

CC(C)(C)OC(=O)N(CCCCCCC(=O)O)CCOCCN=[N+]=[N-]

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 1/20 0.38
L3MBTL1 Q9Y468 4/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
FOLH1 Q04609 3/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24068389 1.00 CA14 (0.38) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765710 0.99 CA14 (0.38) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765717 0.99 CA14 (0.38) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765708 0.99 CA14 (0.38) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765703 0.99 CA14 (0.39) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765713 0.98 CA14 (0.38) CA14L3MBTL1HDAC1HDAC2HDAC6
SCHEMBL23765711 0.95 CA14 (0.37) CA14L3MBTL1
SCHEMBL23765702 0.94 CA14 (0.36) CA14
SCHEMBL23765716 0.90 CA14 (0.36) CA14
SCHEMBL25755913 0.90 CA14 (0.33) CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM EUBULUS BIOTHERAPEUTICS INC. (CN) 2021-12-02 US disclosed
EP-3865152-A1 TARGETED PROTEASE DEGRADATION PLATFORM Eubulus Biotherapeutics Inc. (CN) 2021-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369853-A1 TARGETED PROTEASE DEGRADATION PLATFORM PSMB1, MDM2, XIAP CA14 1481/4885L3MBTL1 278/4885HDAC1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.