Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25756224 | 0.98 | TSHR (0.39) | MEN1KMT2ATSHRMAPK1TTR | |
| SCHEMBL24068407 | 0.86 | TTR (0.39) | MEN1KMT2ATSHRMAPK1TTR | |
| SCHEMBL25756358 | 0.83 | TSHR (0.36) | TSHRTTRALDH1A1KDM4E | |
| SCHEMBL19860326 | 0.82 | TTR (0.37) | TTRKDM4E | |
| SCHEMBL30780885 | 0.82 | TTR (0.37) | TTRKDM4E | |
| SCHEMBL13449860 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL16899883 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL17836995 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL13554631 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL16437097 | 0.80 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865152-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2021-08-18 | — | — | EP | disclosed |