Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.54 |
| ▸ | ESRRA | P11474 | 7/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23424201 | 0.89 | ESR1 (0.51) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23424259 | 0.87 | ESR1 (0.45) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23765847 | 0.85 | ESR1 (0.50) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23765681 | 0.82 | ESR1 (0.61) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL25627260 | 0.82 | ESR1 (0.43) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL25504908 | 0.81 | ESR1 (0.61) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL25476748 | 0.81 | ESR1 (0.61) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23765923 | 0.80 | ESR1 (0.52) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL26462514 | 0.79 | ESR1 (0.62) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL26462167 | 0.79 | ESR1 (0.56) | ESR1ESRRAESR2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | KI PHARMACEUTICALS, LLC | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253626-A1 | PRODRUGS OF FULVESTRANT | CYP19A1, PGR, CYP21A2 | ESR1 9/4885ESRRA 46/4885ESR2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.