SCHEMBL23765984

SCHEMBL23765984

O=CNCCOCCOCCOCCNCCC(=O)Nc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.53
▸ MAP1LC3B Q9GZQ8 7/20 0.51
▸ CRBN Q96SW2 12/20 0.50
▸ BRD4 O60885 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23766094 0.95 STAT3 (0.52) STAT3MAP1LC3BCRBNBRD4
SCHEMBL25031672 0.95 STAT3 (0.51) STAT3MAP1LC3BCRBNBRD4
SCHEMBL23766204 0.91 STAT3 (0.54) STAT3MAP1LC3BCRBNBRD4
SCHEMBL25029989 0.91 STAT3 (0.54) STAT3MAP1LC3BCRBNBRD4
SCHEMBL25031878 0.91 STAT3 (0.53) STAT3MAP1LC3BCRBNBRD4
SCHEMBL23766003 0.91 STAT3 (0.53) STAT3MAP1LC3BCRBNBRD4
SCHEMBL25031671 0.90 STAT3 (0.56) STAT3MAP1LC3BCRBNBRD4
SCHEMBL24068471 0.88 STAT3 (0.54) STAT3MAP1LC3BCRBNBRD4
SCHEMBL24068601 0.88 STAT3 (0.54) STAT3MAP1LC3BCRBNBRD4
SCHEMBL24068298 0.87 STAT3 (0.52) STAT3CRBNBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865152-A1 TARGETED PROTEASE DEGRADATION PLATFORM Eubulus Biotherapeutics Inc. (CN) 2021-08-18 — — EP disclosed
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